Pilot 1: 
Lung-on-Chip & Digital Twin Systems

Who?

University of Galway 

What?

• Lung-on-Chip: Development and validation of a microfluidic model for Acute Lung Injury (ALI) using patient serum
• Digital Twin: In silico simulation of lung–kidney function based on ICU data to predict fluid shifts from drug treatments

Objective?

Demonstrate human-relevant, non-animal models for respiratory and renal conditions to improve drug prediction and reduce clinical trial failure 

SME Involvement?

• Microfluidics or simulation tech developers
• Pharma/biotech SMEs with drug candidates, PK/dose-response data
• Digital health and modelling tool providers